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產品描述： Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for migraine headache research |
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靶點：
5-HT1D Receptor：17 nM (Ki)；5-HT1B Receptor：27 nM (Ki)；5-HT1A Receptor：100 nM (Ki);5-HTReceptor |
參考文獻：
1. S J Peroutka, et al. Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sites. Eur J Pharmacol. 1989 Apr 12;163(1):133-6. 2. K L Dechant, et al. Sumatriptan. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and cluster headache. Drugs. 1992 May;43(5):776-98. |
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溶解性：
H2O : ≥ 100 mg/mL (241.84 mM)DMSO : 50 mg/mL (120.92 mM; Need ultrasonic) |
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保存條件：
2-8℃ |
配置溶液濃度參考：
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1mg |
5mg |
10mg |
| 1 mM |
2.418 ml |
12.092 ml |
24.184 ml |
| 5 mM |
0.484 ml |
2.418 ml |
4.837 ml |
| 10 mM |
0.242 ml |
1.209 ml |
2.418 ml |
| 50 mM |
0.048 ml |
0.242 ml |
0.484 ml |
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| 注意： |
部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。 |
上海工商
危險品化學品經營許可證（不帶存儲）
營業執照(三證合一)
北京