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Tyrphostin 9

    98%

Tyrphostin 9

源葉(MedMol)
S80057
10537-47-0
C18H22N2O
282.38
MFCD00209853
Tyrphostin AG 17, Malonaben, NSC 242557, RG-50872;Propanedinitrile, 2-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-
品牌 貨號 產品規格 價格(RMB) 庫存（上海） 北京 武漢 南京 購買數量
源葉(MedMol) S80057-10mg 98% ￥160.00元 >10 - - -
源葉(MedMol) S80057-50mg 98% ￥288.00元 6 - - -
源葉(MedMol) S80057-100mg 98% ￥560.00元 6 - - -
源葉(MedMol) S80057-200mg 98% ￥1040.00元 預計交期：2-3天 - - -
產品介紹 參考文獻 質檢證書(COA) 摩爾濃度計算器 相關產品

產品介紹

Tyrphostin A9, a PDGFR inhibitor, is a potent inducer of mitochondrial fission. Tyrphostin A9 emerged as the most potent and selective of 51 tyrosine kinase inhibitors tested against the TNF-induced respiratory burst. Tyrphostin A9 has anti-influenza virus activities.
產品描述： Tyrphostin A9, a PDGFR inhibitor, is a potent inducer of mitochondrial fission. Tyrphostin A9 emerged as the most potent and selective of 51 tyrosine kinase inhibitors tested against the TNF-induced respiratory burst. Tyrphostin A9 has anti-influenza virus activities.
靶點： VEGFRInfluenza Virus;PDGFR;EGFR;VEGFR;InfluenzaVirus;PDGFR
參考文獻： 1. Park SJ, Park YJ, Shin JH, et al. A receptor tyrosine kinase inhibitor, Tyrphostin A9 induces cancer cell death through Drp1 dependent mitochondria fragmentation. Biochem Biophys Res Commun. 2011 May 13;408(3):465-70. 2. Richard F. Loeser, Christopher B. Forsyth, Allen M. Samarel et al. Fibronectin Fragment Activation of Proline-rich Tyrosine Kinase PYK2 Mediates Integrin Signals Regulating Collagenase-3 Expression by Human Chondrocytes through a Protein Kinase C-dependen 3. Michele Fuortes, Maxine Melchior, Hyunsil Han, et al. Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF. J Clin Invest. 1999;104(3):327-335. 4. Johan Thyberg . Tyrphostin A9 and wortmannin perturb the Golgi complex and block proliferation of vascular smooth muscle cells. European Journal of Cell Biology.1998,76(1): 33-42 5. R Marhaba, F Mary, C Pelassy, et al. Tyrphostin A9 inhibits calcium release-dependent phosphorylations and calcium entry via calcium release-activated channel in Jurkat T cells. The Journal of Immunology. 1996,157 (4): 1468-1473 6. Kumar N, et al. Receptor tyrosine kinase inhibitors block multiple steps of influenza a virus replication. J Virol. 2011 Mar;85(6):2818-2
溶解性： DMSO  :  50  mg/mL  (177.07  mM;  Need  ultrasonic)    H2O  :  <  0.1  mg/mL  (insoluble)
保存條件： -20℃
配置溶液濃度參考：
1mg 5mg 10mg
1 mM 3.541 ml 17.707 ml 35.413 ml
5 mM 0.708 ml 3.541 ml 7.083 ml
10 mM 0.354 ml 1.771 ml 3.541 ml
50 mM 0.071 ml 0.354 ml 0.708 ml
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參考文獻

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摩爾濃度計算器

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