產品描述: Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. |
靶點:
5-HT3 Receptor;5-HTReceptor |
參考文獻:
1. Faria C, et al. Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis. Am Health Drug Benefits. 2014 Jan;7(1):50-8. 2. Schwartzberg L, et al. Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV). Support Care Cancer. 2014 Feb;22(2):469-77. |
溶解性:
DMSO : ≥ 300 mg/mL (924.87 mM) |
保存條件:
2-8℃ |
配置溶液濃度參考:
|
1mg |
5mg |
10mg |
1 mM |
3.083 ml |
15.414 ml |
30.829 ml |
5 mM |
0.617 ml |
3.083 ml |
6.166 ml |
10 mM |
0.308 ml |
1.541 ml |
3.083 ml |
50 mM |
0.062 ml |
0.308 ml |
0.617 ml |
|
注意: |
部分產品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。 |