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Prulifloxacin

    95%

Prulifloxacin

源葉(MedMol)
S80207
123447-62-1
C21H20FN3O6S
461.463
普盧利沙星; 6-氟-1-甲基-7-[4-(5-甲基-2-氧代-1,3-二氧雜環戊烯-4-基)-甲基-1-哌啶基]-4-氧代-4H-[1,3]硫氮雜環丁烷并[3,2-a]喹啉-3-羧酸; 6-氟-1-甲基-7-{4-(5-甲基-2-氧代-1,3-二噁茂烷-4-基)-甲基-1-哌啶基}-4-氧代-1H,4H-[1,3]噻啶并[3,2-A]-3-喹啉羧酸;;nm441; Sword; Quisnon;
品牌 貨號 產品規格 價格(RMB) 庫存（上海） 北京 武漢 南京 購買數量
源葉(MedMol) S80207-25mg 95% ￥96.00元 >10 - - -
源葉(MedMol) S80207-100mg 95% ￥224.00元 >10 - - -
源葉(MedMol) S80207-500mg 95% ￥480.00元 >10 - - -
產品介紹 參考文獻(1篇) 質檢證書(COA) 摩爾濃度計算器 相關產品

產品介紹

Prulifloxacin (NM441) is an orally active fluoroquinolone antibiotic with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a prodrug of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis
產品描述： Prulifloxacin (NM441) is an orally active fluoroquinolone antibiotic with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a prodrug of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis
靶點： Quinolone;Topoisomerase;Antibacterial;Antibiotic
體內研究： After oral administration of NM441 at a dose of 20 mg/kg to dogs, the peak concentration of NM394 in plasma was 2.39 micrograms/ml, whereas it was 0.63 micrograms/ml for NM394 administered alone. NM441 was as effective as ofloxacin and was twice as effective as ciprofloxacin against systemic infection with Staphylococcus aureus. Against infections with streptococci, NM441 was two to three times as effective as ofloxacin and five times as effective as ciprofloxacin
參考文獻： 1. M Ozaki, et al. In vivo evaluation of NM441, a new thiazeto-quinoline derivative. Antimicrob Agents Chemother. 1991 Dec;35(12):2496-9. 2. Guillem Prats, et al. Prulifloxacin: a new antibacterial fluoroquinolone. Expert Rev Anti Infect Ther. 2006 Feb;4(1):27-41.
溶解性： DMSO  :  12.5  mg/mL  (27.09  mM;  Need  ultrasonic)
保存條件： -20℃
配置溶液濃度參考：
1mg 5mg 10mg
1 mM 2.167 ml 10.835 ml 21.67 ml
5 mM 0.433 ml 2.167 ml 4.334 ml
10 mM 0.217 ml 1.084 ml 2.167 ml
50 mM 0.043 ml 0.217 ml 0.433 ml
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批號：JS298415 貨號：S20001-25g
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摩爾濃度計算器

質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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