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XMD16-5 98%

XMD16-5

源葉(MedMol)
S80287
1345098-78-3
C23H24N6O2
416.47566
品牌 貨號(hào) 產(chǎn)品規(guī)格 價(jià)格(RMB) 庫存(上海) 北京 武漢 南京 購買數(shù)量
源葉(MedMol) S80287-1mg 98% ¥220.00元 10 - - -
源葉(MedMol) S80287-2mg 98% ¥350.00元 10 - - -
源葉(MedMol) S80287-5mg 98% ¥500.00元 7 - - -
源葉(MedMol) S80287-10mg 98% ¥890.00元 6 - - -
源葉(MedMol) S80287-25mg 98% ¥1800.00元 5 - - -
源葉(MedMol) S80287-50mg 98% ¥3200.00元 預(yù)計(jì)交期:2-3天 - - -
源葉(MedMol) S80287-100mg 98% ¥4900.00元 預(yù)計(jì)交期:2-3天 - - -
產(chǎn)品介紹 參考文獻(xiàn) 質(zhì)檢證書(COA) 摩爾濃度計(jì)算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

XMD16-5 is a potent TNK2 inhibitor with IC50 values of 16 and 77 nM for the D163E and R806Q mutations, respectively.
產(chǎn)品描述: XMD16-5 is a potent TNK2 inhibitor with IC50 values of 16 and 77 nM for the D163E and R806Q mutations, respectively.
靶點(diǎn): IC50: 16 nM (TNK2, D163E mutation), 77 nM (TNK2, R806Q mutation);Tyrosinase;PPAR
體外研究:
XMD16-5 potently inhibits the growth of the TNK2 mutant expressing cell lines while having little or no effect on the control cells out to the highest tested concentrations (1,000 nM). XMD16-5 has IC50s of 16 nM and 77 nM for the D163E and R806Q mutations. The effects of XMD16-5 on TNK2 cell lines are largely due to on-target effects on TNK2. Auto-phosphorylation of overexpressed TNK2 mutants could be blocked with TNK2 inhibitor XMD16-5
參考文獻(xiàn):
1. Maxson JE, et al. Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis.
溶解性: soluble  in  DMSO
保存條件: -20℃
配置溶液濃度參考:
1mg 5mg 10mg
1 mM 2.401 ml 12.006 ml 24.011 ml
5 mM 0.48 ml 2.401 ml 4.802 ml
10 mM 0.24 ml 1.201 ml 2.401 ml
50 mM 0.048 ml 0.24 ml 0.48 ml
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參考文獻(xiàn)

質(zhì)檢證書(COA)

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摩爾濃度計(jì)算器

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