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Cidofovir

    
98%

Cidofovir

源葉(MedMol)
S80383 一鍵復制產品信息
149394-66-1
C8H14N3O6P
279.187
西多福韋二水合物;西多福韋 二水;Cidofovir hydrate (1:2);P-[[(1S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid hydrate (1:2);Cidofovir hydrate;Drg-0145;Gs-0504;Phosphonic acid, (
貨號 規格 價格 上海 北京 武漢 南京 購買數量
S80383-10mg 98% ¥148.00 貨期:2-3天 - - -
S80383-50mg 98% ¥290.00 1 - - -
S80383-100mg 98% ¥470.00 貨期:2-3天 - - -
S80383-1g 98% ¥1955.00 貨期:2-3天 - - -
產品介紹 參考文獻 質檢證書(COA) 摩爾濃度計算器 相關產品

產品介紹

Cidofovir is an anti-CMV drug, It can suppress CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. idofovir is an injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis- an infection of the retina of the eye in people with AIDS

產品描述: Cidofovir is an anti-CMV drug, It can suppress CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. idofovir is an injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis- an infection of the retina of the eye in people with AIDS
體內研究: Cidofovir (5 mg/kg/day) subcutaneously for 5 days significantly reduces average virus infectivity titer in blood, spleen, lung and salivary gland in infected guinea pigs. Cidofovir significantly reduces lymphocytosis and average tissue indexe of spleen in infected animals. Cidofovir suppresses all manifestations (skin lesions, paralysis of the hind legs, and mortality) of hairless mice infected intracutaneously with HSV-1 or HSV-2. The most remarkable feature of Cidofovir is that a single administration of the compound, even as late as 4 days after infection, conferees significant protection against HSV-1 or HSV-2 infection. Cidofovir inhibits growth of the highly aggressive melanoma tumor arising from mouse melanoma B16 cells grafted subcutaneously in C57B16/J mice.
參考文獻: 1.Redondo P, et al. Br J Dermatol, 2000, 143(4), 741-748. 2.Li SB, et al. Antiviral Res, 1990, 13(5), 237-252. 3.Snoeck R, et al, Antimicrob Agents Chemother, 1988, 32(12), 1839-1844. 4.Chatterjee S, et al. Antiviral Res., 1992, 19(3), 181-192. 5.De Clercq E, et al. Antimicrob Agents Chemother, 1991, 35(4), 701-706.
溶解性: H2O:10  mM    DMSO:Insoluble
保存條件: 2-8℃
配置溶液濃度參考:
1mg 5mg 10mg
1 mM 3.582 ml 17.909 ml 35.818 ml
5 mM 0.716 ml 3.582 ml 7.164 ml
10 mM 0.358 ml 1.791 ml 3.582 ml
50 mM 0.072 ml 0.358 ml 0.716 ml
注意: 部分產品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。

參考文獻

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