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產品描述： Carbidopa ((S)-(-)-Carbidopa), a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa inhibits pancreatic cancer cell and tumor growth |
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靶點：
Aryl Hydrocarbon Receptor;Decarboxylase;?ArylHydrocarbonReceptor |
體內研究：
Carbidopa also induces nuclear uptake of the AhR, and in vivo studies show that carbidopa at a dose of 1 mg/mouse significantly inhibits tumor growth in athymic nude mice bearing BχPC3 cells as xenografts |
參考文獻：
1. Safe S. Carbidopa: a selective Ah receptor modulator (SAhRM). Biochem J. 2017;474(22):3763-3765. Published 2017 Nov 6. 2. Fermaglich J. Treatment of Parkinson's disease with carbidopa, a peripheral decarboxylase inhibitor, and levodopa. Med Ann Dist Columbia. 1974;43(12):587-591. |
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溶解性：
DMSO : 10 mg/mL (44.20 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble) |
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保存條件：
2-8℃ |
配置溶液濃度參考：
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1mg |
5mg |
10mg |
| 1 mM |
4.42 ml |
22.101 ml |
44.203 ml |
| 5 mM |
0.884 ml |
4.42 ml |
8.841 ml |
| 10 mM |
0.442 ml |
2.21 ml |
4.42 ml |
| 50 mM |
0.088 ml |
0.442 ml |
0.884 ml |
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| 注意： |
部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。 |
上海工商
危險品化學品經營許可證（不帶存儲）
營業執照(三證合一)
北京